Breast Cancer and Genetics

🔬 Approximately 30% of breast cancer cases are linked to genetics.

Gene mutations that increase the risk of cancer are only detected in 5% of cases.

✅ It's important to know:

The risk of breast cancer is a combination of genetics, hormones, lifestyle, and the environment.

👩‍⚕️ Options when mutations are detected:

• Intensive early diagnosis
• Mastectomy and consideration of ovarian removal

🔎 Early diagnostic tactics:

• High risk (40%+) mutations in BRCA1/2, TP53:

Screening every 6 months from age 25, annual MRI, mammography from age 40.

• Moderate risk (21-40%) mutations in CHEK2, RAD51C, ATM:

Annual ultrasound and MRI from age 30, mammography every 1-2 years from age 40.

• Low risk (11-20%) mutations in TOX3, FGFR2:

Early diagnosis from age 30, annual ultrasound and MRI, mammography from age 40.

📌 Note:

Breast removal reduces the risk of cancer by up to 98%, but it is an emotionally challenging decision.

Specialized centers in Germany offer consultations on this matter.